Depin-E Retard is well tolerated in most of the patients. Side effects are generally not serious and do not require discontinuation of therapy. Most of the side effect are expected consequences of the vasodilator effect of Nifedipine. The side effects seen with Depin-E Retard are dizziness, light headedness, giddiness, flushing, headache, weakness, nausea, peripheral oedema, palpitations and nasal stuffiness. Transient hypotension or rarely increase in angina may occur. Nifedipine may increase plasma digoxin levels and may cause glucose intolerance.
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